Ropinirole, a New ALS Drug Candidate Developed Using iPSCs
نویسندگان
چکیده
منابع مشابه
A yeast functional screen predicts new candidate ALS disease genes.
Amyotrophic lateral sclerosis (ALS) is a devastating and universally fatal neurodegenerative disease. Mutations in two related RNA-binding proteins, TDP-43 and FUS, that harbor prion-like domains, cause some forms of ALS. There are at least 213 human proteins harboring RNA recognition motifs, including FUS and TDP-43, raising the possibility that additional RNA-binding proteins might contribute...
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ژورنال
عنوان ژورنال: Trends in Pharmacological Sciences
سال: 2020
ISSN: 0165-6147
DOI: 10.1016/j.tips.2019.12.002